The Bradford Hill Criteria are commonly used as a checklist to argue for causality when randomized trials aren’t possible. However, the originator of these viewpoints never intended for them to be used this way. In this post, I examine the shortcomings of using these viewpoints as a checklist in the real world.
Recently, a giant paper on carbohydrate consumption and mortality was published in The Lancet. The paper discussed the findings of a prospective cohort study and a meta-analysis of several cohort studies. Studies like this are often the ones that generate the most hype, which is always bizarre to me given